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About Me: It comes as a tablet to take by mouth and injection to be administered through a vein. To treat pulmonary arterial hypertension it is usually taken three times a day. PO- 50 mg about 1 hour before sexual intercourse. Adjust Buy Bigfun 100mg dose based on response. Max: 100 mgdose and not more than once in 24 hour. Pulmonary Arterial Hypertension- 20 mg 3 times daily. IV- 10 mg (12.5 mL) administered as a bolus injection 3 times daily.